Search results for " Computer-Assisted]"

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Training labels for hippocampal segmentation based on the EADC-ADNI harmonized hippocampal protocol

2015

Abstract Background The European Alzheimer's Disease Consortium and Alzheimer's Disease Neuroimaging Initiative (ADNI) Harmonized Protocol (HarP) is a Delphi definition of manual hippocampal segmentation from magnetic resonance imaging (MRI) that can be used as the standard of truth to train new tracers, and to validate automated segmentation algorithms. Training requires large and representative data sets of segmented hippocampi. This work aims to produce a set of HarP labels for the proper training and certification of tracers and algorithms. Methods Sixty-eight 1.5 T and 67 3 T volumetric structural ADNI scans from different subjects, balanced by age, medial temporal atrophy, and scanner…

MaleEpidemiologyIntraclass correlationpathology [Cognitive Dysfunction]methods [Pattern Recognition Automated]Hippocampal formationHippocampusFunctional LateralityPattern Recognition Automatedpathology [Alzheimer Disease]ddc:616.89methods [Magnetic Resonance Imaging]methods [Image Processing Computer-Assisted]Image Processing Computer-AssistedSegmentationHARPAged 80 and overmedicine.diagnostic_testHealth PolicyOrgan SizeMiddle AgedMagnetic Resonance Imaginginstrumentation [Magnetic Resonance Imaging]Temporal LobePsychiatry and Mental healthFemalePsychologymethods [Neuroimaging]Algorithmsmethods [Imaging Three-Dimensional]anatomy & histology [Hippocampus]educationNeuroimagingTemporal lobeCellular and Molecular NeuroscienceImaging Three-DimensionalDevelopmental NeuroscienceNeuroimagingAlzheimer DiseasemedicineHumansCognitive Dysfunctionddc:610AgedProtocol (science)business.industryReproducibility of ResultsMagnetic resonance imagingpathology [Temporal Lobe]pathology [Hippocampus]Neurology (clinical)Geriatrics and GerontologyAtrophyNuclear medicinebusinessNeuroscience
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Reference standard space hippocampus labels according to the European Alzheimer's Disease Consortium–Alzheimer's Disease Neuroimaging Initiative harm…

2017

Abstract Introduction A harmonized protocol (HarP) for manual hippocampal segmentation on magnetic resonance imaging (MRI) has recently been developed by an international European Alzheimer's Disease Consortium–Alzheimer's Disease Neuroimaging Initiative project. We aimed at providing consensual certified HarP hippocampal labels in Montreal Neurological Institute (MNI) standard space to serve as reference in automated image analyses. Methods Manual HarP tracings on the high-resolution MNI152 standard space template of four expert certified HarP tracers were combined to obtain consensual bilateral hippocampus labels. Utility and validity of these reference labels is demonstrated in a simple …

Magnetic Resonance Imaging/methods/standardsMaleJaccard indexEpidemiologyComputer sciencemethods [Pattern Recognition Automated]Image ProcessingAutomated/methods/standardsHippocampusPattern Recognition Automatedddc:616.89methods [Magnetic Resonance Imaging]0302 clinical medicinemethods [Image Processing Computer-Assisted]Image Processing Computer-AssistedComputer-Assisted/methods/standardsHARPdiagnostic imaging [Hippocampus]Health Policy05 social sciencesOrgan SizeReference StandardsMagnetic Resonance ImagingHippocampal segmentationstandards [Image Processing Computer-Assisted]Psychiatry and Mental healthNeuroimaging/methods/standardsFemalemethods [Neuroimaging]Hippocampus/diagnostic imagingAlzheimer's Disease Neuroimaging InitiativeAlzheimer Disease/diagnostic imagingNeuroimagingPattern Recognition050105 experimental psychology03 medical and health sciencesCellular and Molecular NeuroscienceDevelopmental NeuroscienceNeuroimagingAlzheimer DiseaseHumans0501 psychology and cognitive sciencesddc:610Reference standardsAgedProtocol (science)standards [Magnetic Resonance Imaging]business.industryPattern recognitionGold standard (test)Neurology (clinical)Artificial intelligenceGeriatrics and Gerontologybusinessdiagnostic imaging [Alzheimer Disease]standards [Pattern Recognition Automated]Neurosciencestandards [Neuroimaging]030217 neurology & neurosurgeryAlzheimer's & Dementia
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The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance : Evidence of validity

2014

BackgroundAn international Delphi panel has defined a harmonized protocol (HarP) for the manual segmentation of the hippocampus on MR. The aim of this study is to study the concurrent validity of the HarP toward local protocols, and its major sources of variance.MethodsFourteen tracers segmented 10 Alzheimer's Disease Neuroimaging Initiative (ADNI) cases scanned at 1.5 T and 3T following local protocols, qualified for segmentation based on the HarP through a standard web-platform and resegmented following the HarP. The five most accurate tracers followed the HarP to segment 15 ADNI cases acquired at three time points on both 1.5 T and 3T.ResultsThe agreement among tracers was relatively low…

MalePathologyDiagnostic criteriaEpidemiologyImage Processinggenetics [Alzheimer Disease]HippocampusFunctional LateralityImagingpathology [Alzheimer Disease]ddc:616.89methods [Magnetic Resonance Imaging]Computer-AssistedClinical trialsddc:150methods [Image Processing Computer-Assisted]ValidationImage Processing Computer-AssistedSegmentationHARPmedicine.diagnostic_testHealth PolicyOrgan SizeAlzheimer's diseaseMiddle Agedinstrumentation [Magnetic Resonance Imaging]Manual segmentationMagnetic Resonance ImagingPsychiatry and Mental healthMagnetic resonanceBiomedical ImagingManual segmentationFemalemethods [Neuroimaging]methods [Imaging Three-Dimensional]EADC-ADNI Working Group on The Harmonized Protocol for Manual Hippocampal Volumetry and for the Alzheimer's Disease Neuroimaging Initiativemedicine.medical_specialtyHippocampal volumetry; Magnetic resonance; Alzheimer's disease; Biomarkers; Diagnostic criteria; Enrichment; Clinical trials; Validation; Harmonized protocol; Standard operating procedures; Manual segmentationConcurrent validityClinical SciencesHarmonized protocolNeuroimagingArticleHippocampal volumetryCellular and Molecular NeuroscienceImaging Three-DimensionalDevelopmental NeuroscienceNeuroimagingClinical ResearchAlzheimer DiseasemedicineHumansddc:610AgedProtocol (science)ReproducibilityInternetbusiness.industryNeurosciencesReproducibility of ResultsMagnetic resonance imagingBrain DisordersStandard operating procedurespathology [Hippocampus]EnrichmentGeriatricsThree-DimensionalNeurology (clinical)Geriatrics and GerontologyAtrophyNuclear medicinebusinessBiomarkers
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